Signs and symptoms of paraneoplastic syndromes of the nervous system usually develop relatively quickly, often over days to weeks. Signs and symptoms vary depending on the body part being injured, and may include: • Difficulty walking • Difficulty maintaining balance • Loss of muscle tone or weakness • Loss of fine motor skills • Difficulty swallowing • Slurred speech • Memory loss • Vision problems
Common paraneoplastic syndromes of the nervous system include:
1. Cerebellar degeneration. This is the loss of nerve cells in the area of the brain that controls muscle functions and balance (cerebellum).
2. Limbic encephalitis. This is inflammation affecting a region of the brain known as the limbic system, which controls emotions, behaviors and certain memory functions.