Tuberculosis, commonly known as TB, is a bacterial infection that can spread through the lymph nodes and bloodstream to any organ in your body mostly lungs.
In 2011 a total of 10,528 new TB cases were reported in the United States. This is an incidence of 3.4 cases per 100,000 population, which is 6.4% lower than the rate in 2010, and the lowest rate recorded since national reporting began in 1953.
Treatment of TB uses antibiotics to kill the bacteria. Effective TB treatment is difficult, due to the unusual structure and chemical composition of the mycobacterial cell wall.
The BCG vaccine has limitations, and research to develop new TB vaccines is ongoing. A number of potential candidates are currently in phase I and II clinical trials.