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Journal of Clinical & Experimental Pharmacology | ISSN: 2161-1459 | Volume: 8

International Conference on

July 18-19, 2018 | Atlanta, USA

Pharmacology and Ethnopharmacology

International Conference and Exhibition on

Pharmaceutical Oncology

Antibacterial activity of Commiphora gileadensis

and

Abutilon bidentatum

, collected from Al-

Abwa region, Saudi Arabia

Amal Y Aldhebiani

and

Magda M Aly

1,2

King Abdulaziz University, Saudi Arabia

Kafr el-Sheikh University, Egypt

ifferent plants have been traditionally used in folkloric medicine to treat many diseases and disorders or to improve

human health due to their secondary metabolites which have excellent antimicrobial activities.

Commiphora gileadensis

and

Abutilon bidentatum

were collected from Al-Abwa region, Saudi Arabia, identified, extracted and their antibacterial

activity was determined by agar well diffusion method. Extraction by methanol, ethanol, acetone and hot water was carried

out and some multidrug-resistant bacteria were used as test bacteria. Maximum activity was recorded for the methanolic

extract against all tested bacteria with inhibition zone diameter ranged from 31-35 mm and MIC was ranged 37.5 µg/ml. The

lowest activities were recorded for the water extracts of the two plants

Commiphora gileadensis

, and

Abutilon bidentatum

extract showed weaker antimicrobial activity against the tested bacteria compared to

C. gileadensis

leave

extracts. It is noticed that

C. gileadensis

stem extracts showed stronger antimicrobial activity. The methanolic extracts of the

two tested plants have no toxicity using

Artemia salina

as a test organism. In conclusion,

C. gileadensis

and

A. bidentatum

can

be traditionally and safely used against multidrug-resistant bacteria due to the efficient antimicrobial activities and low toxicity.

Biography

Amal Y Aldhebiani, associate professor in Plant Taxonomy, Biological Sciences Dept. Jeddah, Kingdom of Saudi Arabia. PhD from University of Reading, United

Kingdom. Research interest in Flora of Saudi Arabia and medicinal plant in the country, their taxonomy and uses. Phytochemical compounds analysis and their

application. Genetic diversity among medicinal plant and how would that affect the chemical constituents and the environmental relation.

aaldhebiani@kau.edu.sa

Amal Y Aldhebiani et al., Clin Exp Pharmacol 2018, Volume: 8

DOI: 10.4172/2161-1459-C1-029