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Volume 8, Issue 5 (Suppl)
J Chromatogr Sep Tech, an open access journal
ISSN: 2157-7064
Chromatography 2017
August 07-09, 2017
August 07-09, 2017 | Rome, Italy
4
th
World Congress on
Chromatography
Chromatographic monitoring of febantel after biodegradation and advanced oxidation processes
Danijela Ašperger
1
, Josipa Papac
1
, Mirta Čizmić
1
, Sandra Babić
1
, Tibela Landeka Dragičević
1
, Davor Ljubas
1
, Lidija Ćurković
1
and
Sanja Radman
2
1
University of Zagreb, Croatia
2
Pliva d.o.o., Croatia
C
lassical methods of wastewater treatment fail to remove small molecules of contaminants such as pharmaceuticals. For
many years pharmaceuticals have been used for medical therapeutic purposes and therefore have been uncontrollably
released in the environment, through excretion, inappropriate disposal or because of inadequate waste water treatment.
Recently, they have been recognized as potentially harmful pollutants, so accordingly the term emerging contaminants has
been formed. One of commonly used pharmaceuticals is the anthelmintics whose representative is febantel. Febantel is used
in human medicine and in veterinary practice very often. In spite of its frequent usage, about febantel behavior during and
after wastewater treatment, there are still no sufficient data to predict its behavior and possible impact on the environment.
The goal of this paper was monitoring the degradation products of febantel after biodegradation with activated sludge and
compares them with the degradation products obtained after advanced oxidation processes (AOPs), so that, it can be used in
system for waste water treatment. The effectiveness of febantel degradation and identification of degradation products formed
during the processes was monitored by analytical and bioanalytical methods. Degradation products have been detected and
identified by high and ultra-high performance liquid chromatography coupled to mass spectrometers. Assessment of toxicity
of degradation process was done by measuring the bioluminescence inhibition of
Vibrio fischeri
bioassay. Finally, the results
indicated that degradation products obtained during biodegradation are different from degradation products obtained by
AOPs. Also degradation products after AOPs proved to be more toxic.
Biography
Danijela Ašperger has her expertise in Analytical Chemistry, Environmental Chemistry and, Toxicology. In 2013, she was appointed as an Associate Professor at
Faculty of Chemical Engineering and Technology, University of Zagreb. She is currently working as a participant on the project "Fate of pharmaceuticals in the
environment and during advanced wastewater treatment" funded by Croatian Science Foundation. She teaches instrumental analytical chemistry, characterization
of materials, nondestructive methods of chemical analysis in art and archeology, and quality management.
diva@fkit.hrDanijela Ašperger et al., J Chromatogr Sep Tech 2017, 8:5(Suppl)
DOI: 10.4172/2157-7064-C1-032