genomics-integrative-biology-2018-posters

3 / 31

Page 87
Notes:
conferenceseries.com
Volume 12 Journal of Molecular and Genetic Medicine
ISSN: 1747-0862
May 21-23, 2018 Barcelona, Spain
&
Integrative Biology
6th International Conference on
Genomics and Molecular Biology
10th International Conference on
Genomics 2018 and Integrative Biology 2018
May 21-23, 2018
JOINT EVENT
Genome-wide evaluation of loci and candidate genes underlying important traits in soybean (Glycine
max (L.) Merr.)
Wenbin Li, Xue Zhao,Yingpeng Han, Weili Teng, Jian Luo, Lei Feng and Chanjuan Zhang
Northeast Agricultural University, China
Disease resistance and seed quality are important traits for soybean breeding. Better understanding of the genetic
architecture and genomic landscape of soybean germplasm with targeted traits is the precondition of molecular design
breeding of soybean. Construction of a favorable data platform including phenotyping and genotyping pools and efficient
analytical approaches were the fundamental tasks for molecular breeding work. Therefore, more than 500 diverse soybean
accessions were sequenced using specific-locus amplified fragment sequencing (SLAF-seq) to establish a genotype database.
In total, 64 141 single nucleotide polymorphisms (SNPs) with minor allele frequencies (MAFs) > 0.05 were found among the
512 tested accessions. The genotyped soybean germplasm has been phenotyped for some important soybean quality traits
including soybean fatty acid components and seed vitamin E content under multi-environmental conditions. Resistance to
different pathogens including resistance to soybean cyst nematode (SCN), soybean white mold (SWM), soybean root rot (SRR)
and soybean mosaic virus (SMV) has also been phenotyped. A set of loci were found to be associated with the above traits
by GWAS and some of them were confirmed by bi-parental mapping which has been used for molecular assisted selection
breeding. A set of candidate genes for disease resistance that have been evaluated via sequence polymorphism and differential
expression in special donors were cloned and were staged in functional genomics research.
Biography
Wenbin Li completed his PhD in Plant Genetics and Breeding in 1988 at Northeast Agricultural University of China. He is working at Soybean Research Institute of
Northeast Agricultural University for more than 15 years as a Director and Professor. His major research areas are covered by soybean functional genomics, gene
characteristics for agronomic important traits, and molecular breeding. He has published over 80 peer reviewed papers in numbers of international journals, such as
New Phytologist, The Plant Journal, TAG, BMC Genomics and Heredity. Recently, he became a member of Executive Committee for World Soybean Association,
and an Associate Editor of BMC Genomic.
Wenbin Li et al., J Mol Genet Med 2018, Volume 12
DOI: 10.4172/1747-0862-C2-028