17 / 41
Page 61
Notes:
conferenceseries
.com
Volume 5, Issue 5 (Suppl)
Nat Prod Chem Res
ISSN: 2329-6836 NPCR, an open access journal
Pharmacognosy 2017
July 24-25, 2017
July 24-25, 2017 Melbourne, Australia
5
th
International Conference and Exhibition on
Pharmacognosy, Phytochemistry
& Natural Products
Bioactives profiling of Australian native
Cordycep gunnii
Rashida Bashir, Enzo Palombo and Peter Mahon
Swinburne University of Technology, Australia
C
ordyceps gunnii
, caterpillar fungi growing on insect larvae, has long been known as exotic medicinal fungi. Commercially
available Chinese
Cordyceps
species are very expensive and known to treat cancer, asthma, TB, diabetes, erectile dysfunction
and hepatitis. However, the Australian native
Cordyceps
species, especially
Cordyceps gunnii
, have not been investigated in detail.
Recent investigations of biologically active metabolites of Australian native
Cordyceps gunnii
fungi have indicated their tremendous
potential as a source of new medicines and nutraceuticals. LC-ESI-MS analysis of
Cordyceps gunnii
has demonstrated the presence of
pharmacologically active nucleosides which are known to be responsible for the regulation and modulation of various physiological
and pharmacological actions .They elevate cAMP which results in increase energy levels and protect the body from cardio and
neuropathies. Fatty acid methyl ester (FAME) derivatization followed by GC MS analysis has showed that stearic acid, linoleic acid,
oleic acid, ergosterol and its derivatives, lanosterol and squalene are the main components of natural
Cordyceps gunnii
. Ergosterol is
a provitamin form of vitamin D
2
and squalene has superior antioxidant activity which plays a preventive role against several types of
carcinogenesis. A reaction flow-post column derivatization (RF-PCD) FRAP assay has indicated the presence of strong antioxidant
peaks, which will be further investigated for the characterization of bioactive compounds. Hence, current studies have demonstrated
that Australian native
Cordyceps gunnii
is a promising source of nutraceuticals and pharmaceuticals.
Biography
Rashida Bashir is currently pursuing her PhD in the area of natural products and bioanalytical chemistry. She has previously completed Master’s degree of
Biotechnology and Bachelor’s degree of Pharmaceutical Sciences.
rbashir@swin.edu.auRashida Bashir et al., Nat Prod Chem Res 2017, 5:5 (Suppl)
DOI: 10.4172/2329-6836-C1-017