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Bioavailability (BA) could be a subcategory of absorption associate degreed is that the fraction of an administered dose of unchanged drug that reaches the circulation, one in all the principal pharmacokinetic properties of medicine. By definition, once a medicine is run intravenously, its bioavailability is 100 percent. However, once a medicine is run via different routes (such as orally), its bioavailability usually TH decreases (due to incomplete absorption and first-pass metabolism) or might vary from patient to patient. Bioavailability is one in all the essential tools in materia medica, as bioavailability should be thought of once hard dosages for non-intravenous routes of administration.