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Breast neoplasms represent a significant health concern worldwide, necessitating accurate and timely diagnostic approaches for optimal patient outcomes. Contrast-enhanced ultrasound (CEUS) imaging has emerged as a promising modality for the assessment of breast lesions, offering improved sensitivity and specificity compared to c.. Read More
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Giant cell tumors of the soft tissue are rare entities, and their occurrence within the breast is even more infrequent. This article provides a thorough review of the existing literature on giant cell tumors, focusing specifically on their manifestation in the soft tissue of the breast. Additionally, we present a detailed case r.. Read More
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Novel Obstacles in the Multimodal Exercise Regimen for Locally Advanced Breast Cancer
Multimodal exercise regimens have gained prominence in the comprehensive care of locally advanced breast cancer (LABC) patients. This article explores the emerging challenges encountered in implementing such regimens for individuals facing LABC. As the integration of diverse exercise modalities becomes increasingly prevalent, un.. Read More
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This research explores the relationship between breastfeeding practices and the risk of developing epithelial ovarian cancer in women carrying the BRCA1 or BRCA2 mutation. The BRCA1 and BRCA2 genes are known to be associated with an increased susceptibility to breast and ovarian cancers. However, limited attention has been given.. Read More
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Triple-negative breast cancer (TNBC) is a subtype associated with aggressive clinical behavior and limited therapeutic options. Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) has emerged as a potential biomarker in various cancers, yet its role in TNBC remains unclear. This study aims to investigate the assoc.. Read More
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An Unusual Case of Breast Cancer Scalp Metastasis
Breast cancer is a complex and heterogeneous disease that can metastasize to various organs, with scalp involvement being an uncommon manifestation. This case report presents a rare occurrence of breast cancer metastasis to the scalp in a 56-year-old female patient with a history of invasive ductal carcinoma. The patient present.. Read More
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An Uncommon Sebaceous Carcinoma Outside the Eye that Resembles Primary Ectopic Breast Cancer
Sebaceous carcinoma is a rare malignancy typically associated with the ocular region, particularly the eyelid. However, in this case report, we present an unusual occurrence of sebaceous carcinoma manifesting outside the eye in a manner that closely resembles primary ectopic breast cancer. The patient, a 79-year-old female, pres.. Read More
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Mucinous breast cancer (MBC) represents a distinct histological subtype of breast cancer characterized by the presence of mucin-producing cells within the tumor. This study presents a comprehensive retrospective analysis conducted at a tertiary single-center, aiming to elucidate the clinicopathological characteristics, treatment.. Read More
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Objective: This study investigated whether Background Parenchymal Enhancement (BPE) on imaging is valuable in determining pathological tumour response to neoadjuvant chemotherapy (NAC) amongst breast cancer patients in a tertiary-care hospital Dubai, United Arab Emirates (UAE). Methods: Retrospective data from 64 patients with .. Read More
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Research Question: Is there a significant difference in cumulative serum lipid events between nonsteroidal and steroidal aromatase inhibitors (AIs) in hormone-sensitive postmenopausal early stage breast cancer? Background: Studies estimating the effect of AIs in post-menopausal early breast cancer have demonstrated conflicting .. Read More
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Graphene-Based Multifunctional Nano Systems for Breast Cancer Detection and Therapy
Graphene-based multifunctional nanosystems have emerged as promising tools in the field of breast cancer detection and therapy. Breast cancer remains a significant global health concern, necessitating the development of innovative approaches to enhance early diagnosis and effective treatment. Graphene, with its exceptional elect.. Read More
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Triple negative breast cancer (TNBC) is an aggressive subtype characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) expressions. Tumor-infiltrating lymphocytes (TILs) play a crucial role in the immune response against TNBC, potentially influencing .. Read More
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Immunotherapy, specifically Chimeric Antigen Receptor (CAR) T cell and Fc-receptor-enhanced chimeric receptor (Fc-CR) T cell therapies, has emerged as a promising approach for treating cancer. The development and translation of these therapies from preclinical studies to clinical applications represent a critical phase in their .. Read More
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The mixture remedy with specific therapy modalities has been extensively utilized in the scientific functions of most cancers treatment. However, it stills a widespread task to gain co-delivery of extraordinary pills due to the fact of awesome drug encapsulation mechanisms, low drug loading, and excessive excipient-related toxic.. Read More
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The Prognostic and Predictive Utility of Tumor Infiltrating Lymphocytes in Early Breast Cancer
Tumor-infiltrating lymphocytes (TILs) have emerged as a promising and dynamic area of research in the field of oncology, particularly in the context of early breast cancer. This paper delves into the prognostic and predictive utility of TILs, shedding light on their potential as valuable biomarkers for clinical decision-making. .. Read More
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Lymphangitic carcinomatosis (LC) represents a rare and challenging manifestation of metastatic breast cancer, often associated with poor prognosis and limited treatment options. HER2-positive breast cancer subtype accounts for a significant proportion of metastatic cases, and targeted therapies, such as trastuzumab and pertuzuma.. Read More
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Breast Cancer Stem Cell Antigens as Immunotherapeutic Targets
Breast cancer remains a significant global health challenge, demanding innovative approaches to enhance treatment outcomes. Among these approaches, immunotherapy has gained significant attention. This thesis explores the concept of immunotherapeutic targeting of breast cancer stem cell (BCSC) antigens as a promising strategy to .. Read More
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Breast Cancer Stem Cell Adaptability and Heterogeneity Regulated by Novel Molecular Regulators
Breast cancer is a complex and heterogeneous disease characterized by the presence of breast cancer stem cells (BCSCs). These BCSCs exhibit unique properties, including self-renewal, tumorigenicity, and resistance to therapy, which contribute significantly to disease progression and treatment challenges. Understanding the mechan.. Read More
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Biomarkers for HER2-positive Metastatic Breast Cancer that Go Beyond Hormone Receptors
HER2-positive metastatic breast cancer represents a distinct subtype of breast cancer with aggressive clinical behavior. While the overexpression of human epidermal growth factor receptor 2 (HER2) is a hallmark of this subtype, its heterogeneity necessitates a more nuanced understanding to guide treatment decisions. Beyond tradi.. Read More
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Bacterial and Viral Vectors as Vaccine Delivery Vehicles in the Treatment of Breast Cancer
Breast most cancers is the often identified most cancers amongst ladies and it is the most deadly malignancy in ladies globally. With one million instances each and every year, breast most cancers is the fast-growing most cancers kind that has an excessive incidence fee in younger women. The boundaries and undesirable aspect out.. Read More
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