The clinical practice of orthodontics has changed since I started residency years ago. The basic premise of moving teeth through alveolar bone using bio-mechanical methods within a safe, cellular environment has not changed much. In most clinical scenarios, the most common treatment approaches to correct the malocclusion by providing mechanical forces in a controlled manner.
Kau CH (2012) Biotechnology in Orthodontics Photo Biomodulation. Dentistry 2:e108.