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One of the challenges of antiretroviral treatments (cART) in HIV is to achieve optimal and persistent adherence. In order to achieve this, electronic pill-boxes used in conjunction with motivational interviewing have shown promising results in monitoring and improving patient’s adherence to treatments. This study reports a case where the patient was opening every day on time his pill-box to discard systematically the tablets in order to hide consciously his nonadherence. A too regular pattern in drug intake according to the electronic pill-box should alert health professionals for the potential risk of distorted adherence results.
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