There are several Hepatitis B Journals, of which Internal Medicine Open Access is one. Internal Medicine open access is an omics group journal that is peer reviewed and scholarly open access. The articles are accessible to all the readers around the world for free.
Hepatitis B is a small, partially double-stranded, non-enveloped DNA virus. It matures to a covalently closed circular DNA in the nucleus and can persist in a latent state after resolution of viremia. The likelihood of developing a chronic infection after initial infection is high in neonates and immunocompromised individuals but 5% or less in immunocompetent adults. The intensity of acute liver injury from the viral infection relates to the strength of the immune response. Thus, a healthy adult with a robust immune response to the virus may die of fulminant hepatitis after initial infection while demonstrating low viral titers in the blood. An immunocompromised individual, by contrast, may have little laboratory evidence of liver injury, despite displaying high titers of virus in liver and blood. Patients with serological markers showing cleared hepatitis B infection are at risk of reactivation of the virus when they are immunosuppressed.
Last date updated on July, 2014