Chromosome

Gene Technology is one of the top leading journals in biomedical engineering which publishes novel research articles after rigorous peer-review process by at least 2 expert reviewers of the associated fields. Modern Biotechnology are interesting fields in which expression of genes, taking advantage of natural genetic variation, modifying genes and transferring genes to new hosts, Environmental Biotechnology, Cell biology, Genetic Engineering and Molecular Biology, Tissue Engineering, Biosensor, Cancer Biology, Bioinformatics and Computational biology are covered. The eukaryotic chromosome is linear, with a centromere and telomere. The chromosome replicates from the origin of replication during the S-phase of the cell cycle. The centromere proteins, CENP-A,-B, and -C, located in the centromere sequence, assist with assembly of the kinetochore complex during the M phase. Then, the spindle fiber is attached to the kinetochore, and the chromosome is distributed to both poles. In this way, replicating chromosomes are distributed to daughter cells, and the genomic information of a mother cell is stably transmitted to daughter cells. Physiologically, the same mechanisms are used for the replication and distribution of HAC vectors. "Mitsuo Oshimura, Toward Gene and Cell Therapies Employing Human Artificial Chromosomes in Conjunction with Stem Cells" OMICS is devoted to the prompt publication of original findings of the highest scientific priority and value that provide novel mechanistic insights, represent a clear advance over previous Studies and have the potential to generate exciting future research.

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Last date updated on September, 2024