Thrombocytopenia

Thrombocytopenia is defined as a platelet count below 150*109/l, caused by accelerated platelet destruction or decreased production. It is classified as mild with a platelet count of 100-150*109/l, moderate at 50-100*109/l and severe with less than 50*109/l. Thrombocytopenia is secondly to anaemia as the most common hematologic abnormality during pregnancy. Indeed, a platelet count <150*109/l can be observed in 6 to 15% of pregnant women at the end of pregnancy. Thrombocytopenia is usually moderate (<100*109/l in only 1% of women) and often incidentally detected on routine blood count. Gestational Thrombocytopenia (GT) is considered the most prevalent cause of thrombocytopenia during pregnancy accounting for about 75% of cases. The etiology is unknown, but it is considered to be due to the relative hemodilution of pregnancy, amplified by the capture or destruction of platelets in the placenta. Review articles are the summary of current state of understanding on a particular research topic. They analyze or discuss research previously published by scientist and academicians rather than reporting novel research results. Review article comes in the form of systematic reviews and literature reviews and are a form of secondary literature. Systematic reviews determine an objective list of criteria, and find all previously published original research papers that meet the criteria. They then compare the results presented in these papers. Literature reviews, by contrast, provide a summary of what the authors believe are the best and most relevant prior publications.

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Last date updated on September, 2024