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Histopathologically indicated skin necrosis, hyperplasia in the secondary lamellae of gill, degenerative changes in glomerular epithelium in kidney, vacuolar degeneration in hepatocytes, hyperplasia in the lymph follicles of spleen, edema , and focal hyaline degeneration in muscles. Therefore, routine monitoring of drug susceptibility pattern over time is necessary.
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Last date updated on September, 2024