Mycobacteria are notorious for causing two major human diseases: tuberculosis and leprosy. Both are hard to cure, and TB alone causes more than a million deaths each year. Fortunately, they are very slowly growing bacteria. MTB is difficult to grow in vitro . The mycobacterium leprae, which causes leprosy, is even more difficult to study because it has never been successfully grown in vitro .It is because MTB lives longer than most other bacteria. The principle of nature in the circle of life reveals that the longer the lifespan, the lower the fecundity.There are many studies documented the inverse relationship between the lifespan and the fecundity, such as in the C. Elegans, drosophila, and mice. (Why is Mycobacterium Tuberculosis Hard to Grow? The Principle of Biorelativity Explains- Rui-An Wang)
Last date updated on September, 2024