Pulmonary TB Among Diabetic Patients

Diabetes mellitus (DM) TB co-infection is associated with poor glycemic control in DM patients. Reactive hyperglycemia often accompanies chronic infections due to the associated proinflammatory state and release of counter-regulatory stress hormones such as epinephrine, cortisol and glucagon, all insulin antagonists. Tuberculosis (TB) remains a major source of morbidity and mortality throughout the world; one-third of the worldâ™s population is estimated to be infected with Mycobacterium tuberculosis (MTB), whereby approximately nine million people develop the disease each year, and almost two million die annually as a result. Epidemiological analyses have elucidated an association between DM and the development of TB. Diabetes mellitus (DM) is the most frequent chronic endocrine disorder; it is a non-transmissible pathological entity, characterized by disorders of the entire metabolism but particularly, of carbohydrate metabolism.

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Last date updated on September, 2024