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Pharmacogenetics Reviews

PharmacogeneticsÂ is the discipline that analyses the genetic basis for the interindividual variation in the body disposition of drugsÃ¢â¬Â. The initial candidate genes studies, in which genetic variants of host factors that were already known to play a role in HIV-infection were tested, have led to genome wide association studies (GWAS), in which not only one gene but in fact the whole genome is studied. Sonia RodrÃÂguez NÃÂ³voa, The Pharmacogenetics of HIV Treatment: A Practical Clinical Approach.