|Physical dependence is the state of the body when it becomes so dependent on a drug that the body cells cannot function without it. Withdrawal may lead to complications ranging from headache, vomiting , nausea to delirium, convulsions etc. substances which are capable of producing Physical dependence should not be stopped suddenly but the dose should be lowered gradually. Online Journals are scholarly and peer reviewed journals. The journals provide forum and motivates scientists, researchers, academics, engineers, and practitioners in all aspects to share their professional and academic knowledge in the fields computing, engineering, humanities, economics, social sciences, management, medical science, and related disciplines. Online Journals also aims to reach a large number of readers worldwide with original and current research work completed on the vital issues of the above important disciplines. The journals permit all readers to read, view, download and print the full-text of all published articles without any subscription or restrictions.