The setting of elderly patients, with an underlying baseline state of dementia quite possible, this can trigger the onset of delirium and present in an acute fashion. The mechanism behind Clostridium difficile infection inducing delirium is complex and not fully understood. While the neural correlates of conditions such as post-stroke depression and apathy have been well investigated, confusion, hyperactive delirium, and secondary mania are less well detailed. Right hemispheric post-stroke patients with hyperactive delirium often share similar lesion sites, but also have a greater tendency to involve limbic related medial temporal lobe structures. As a whole, delirium is present in 36-50% of post-stroke patients and one-half of those display psychomotor hyperactivity. Despite this epidemiology, non-agitated confusion, hyperactive delirium, and secondary mania when considered as a spectrum are frequently encountered neuropsychiatric symptoms on inpatient stroke services.
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Last date updated on February, 2021