alexa Hypovitaminosis D|OMICS Group|Alzheimer's Disease And Parkinsonism

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Hypovitaminosis D

Accrued evidence suggesting that hypovitaminosis D acts as a risk factor for developing Parkinson™s disease(PD) remains controversial. Herein we evaluated existing results, and outline several biological mechanisms by which the hypovitaminosis D-PD relationship may occur. We performed a meta-analysis, using data obtained froma search of PubMed from July 2002 to July 2012, for studies reporting serum vitamin D levels in PD and controlpatients.We found that in comparison to healthy individuals, those with PD had lower levels of serum vitamin D. Furthermore, we explore a number of potential associated biological mechanisms, including the actions of reactivenitrogen species (RNS), glutathione (GSH), and glial-derived neurotrophic factor (GDNF) in the brain. The top journals are peer reviewed scholarly journals. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in MEDLINE, PUBMED, SCOPUS, COPERNICUS, CAS, EBSCO and ISI.
 
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