Oxidative Stress (OS) in patients with diabetes characterized by elevation of reactive oxygen species production and decrease of Antioxidative Defense (AOD) level that lead to activation of Lipid Peroxidation (LPO) and oxidative lipoprotein modification with increased atherogenesis. Elevation of CDs and TBARs levels in Caucasian patients with diabetes compare to Mongoloids confirms activation of pro-oxidative processes during lipid peroxidation. Ethnic factor plays one of the most important roles in development of oxidative stress in non-compensated T1D. However, ethnic factor does not play role in lipid peroxidation in healthy people. Ethnicity can play a role in development of oxidative stress in non-compensated type1 diabetes.
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Last date updated on July, 2014