Adjuvant treatments, such as re-operation and gamma knife radiosurgery, are currently indicated for residual tumor, based on postoperative MRI findings. However, it is often difficult to detect an adenoma using MRI. Additionally, the granulation tissue that forms after a surgical procedure increases the difficulty of identifying a residual tumor. Identification of the residual tumor after surgery is important to aid the selection of adjuvant therapy. Considering these limiting factors, the adjuvant therapy that was selected based on MRI findings may prove to be ineffective. In terms of gamma knife adjuvant therapy, the sequential changes in IGF-1 after gamma knife radiosurgery differ between MRI-based dose planning and MET-PET-based dose planning.
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Last date updated on July, 2014