Parkinson disease is degeneration of neuronal degeneration and death of compact part in substantial nigra of mesencephalon, and decreasing release of dopamine in striatum. The etiology is not clear yet. On the aspect of therapy, traditional substitutive therapy of dopamine is majority, levedopa and its compound agent are major medication. Although having neuronal toxical effect of self-oxidation, levodopa cannot be substituted because of its reliable effects.
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Last date updated on January, 2021