In the immunological and glycobiological literature, glycoepitopeâ is often used to specify the carbohydrate moiety that is recognized by an antibody or by a GBP. The antibody-binding glycoepitopes are also classified as B cell epitopes or antigenic determinants. Conceptually, glyco-epitomeâ refers to the entire repertoire of glycoepitopes, including the B cell epitopes and those that are recognized by GBPs. Differing from glycome, which covers all the existing carbohydrate molecules in living organisms, glyco-epitome refers to a unique subset of carbohydrates that serve as the sugar signatures for molecular recognition and bio-signal transmission. Glyco-epitomics is, thus, an evolving area of glycomics research focusing on identifying, characterizing, and understanding the carbohydrate moieties that serve for multiple levels of bio-communication. The structural aspects of glyco-epitomics focus on the elucidation of the glycan structures that display glyco-epitopes. This research area has been substantially enhanced by the development of advanced profiling and structural characterization strategies.
The impact factor of journal provides quantitative assessment tool for grading, evaluating, sorting and comparing journals of similar kind. It reflects the average number of citations to recent articles published in science and social science journals in a particular year or period, and is frequently used as a proxy for the relative importance of a journal within its field. It is first devised by Eugene Garfield, the founder of the Institute for Scientific Information. The impact factor of a journal is evaluated by dividing the number of current year citations to the source items published in that journal during the previous two years.
Last date updated on September, 2024
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