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This article reviews literature regarding smoking cessation in Schizophrenia population, its harmful effects on health, finances, role of mental health care providers and better available options for treatment as are in general population. This population not only smokes at higher rates, but also has higher nicotine dependence with lower cessation rates than general population, people of schizophrenia have truncated life span due to smoking related diseases and premature mortality compared with the general population. Contrary to traditional reasoning that this population is not motivated or able to tolerate smoking cessation, but there is extensive literature that negates such rationale, even provides better treatment options to address this huge public health burden.