Multiple Myeloma (MM) is a common haematological condition primarily affecting older people, with a median age at diagnosis of about 65-70 years and a slight prevalence in male gender and in African-Americans. An abnormal plasma cell growth within the bone marrow accounts for this condition, leading to interference with normal haemopoiesis and excessive production of abnormal monoclonal antibodies (paraprotein). The activation of osteoclasts in the surrounding bone tissue exposes to the risk of pathological fractures and hypercalcemia.
Caldarella C, et al. Treglia G (2013) Treatment Response Monitoring in Patients with Multiple Myeloma: The Role of Positron Emission Tomography- Computed Tomography using Fluorine-18-Fluorodeoxyglucose. J Bone Marrow Res 1: e103. doi: 10.4172/2329-8820.1000e103