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The role of extracellular matrix in lung disease has been an area of increasing research interest. Numerous studies have demonstrated the importance of extracellular matrix in pulmonary pathologies. Evaluation of the intracellular function and basic structural properties of proteoglycan adhesion proteins and structural proteins may reveal new approaches to the treatment of pulmonary disease. This manuscript summarizes the role of extracellular matrix in pulmonary diseases based on the currently available literature.
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