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The Behavior of 3-Anilinoenone and N-Phenyl Cinnamamide toward Carbon Nucleophiles: Spectroscopy and X-Ray Studies Reveal Interesting New Synthesis Routes to Nicotinonitriles and Tetrahydropyridine-3- Carbonitrile

The chemistry of enaminones is recognized as a significant field of study because enaminones serve as both starting materials for the synthesis of various heterocyclic compounds that have potential agrochemical use and as intermediates in dye and pharmaceutical industries.Due to their biological activities and pharmacological properties, pyridines and pyridones represent an important class of compounds that have been developed using functionally substituted enaminones . In continuation of our interest in the synthesis of functionally substituted heteroaromatic compounds such as pyridines and pyridones, utilizing enaminones as starting materials, we report here the behavior of 3-anilinoenone and N-phenyl cinnamamide derivative toward malononitrile in the synthesis of pyridine derivatives.

 

Citation: Al-Omran F, El-Khair A (2014) The Behavior of 3-Anilinoenone and N-Phenyl Cinnamamide toward Carbon Nucleophiles: Spectroscopy and X-Ray Studies Reveal Interesting New Synthesis Routes to Nicotinonitriles and Tetrahydropyridine-3-Carbonitrile. Organic Chem Curr Res 3:123. doi: 10.4172/2161-0401.1000123

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