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Treatment of visual impairment in children with CP is challenging, recent research in this area has shown considerable improvement with the use of stem cells in combination with neurotrophic agents. The use of human embryonic stem cells (hESCs) has been explored recently for the treatment of CVI in children with CP. Although very few studies evaluating the role of hESCs are available due to controversial source and isolation technique of hESCs, a study on visually impaired rates showed 100% improvement with the use of hESCs. The present study assessed the efficacy and safety of hESC therapy in 40 CP children with CVI. Single Photon Emission Computed Tomography (SPECT) scan and an in-house developed scoring system; Nutech Functional Scores (NFS) was used to evaluate the extent of improvement in perfusion before and after treatment with hESCs.
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