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Indications for Implantable Cardioverter-Defibrillator Therapy and Recommendations for Implantable Cardioverter-Defibrillator Therapy in Patients not Included or not Well Represented in Clinical Trials

he American College of Cardiology Foundation (ACCF)/American Heart Association (AHA) guidelines recommend that Class I indications for therapy with an implantable cardioverter defibrillator (ICD) are 1) cardiac arrest due to ventricular fibrillation (VF) or ventricular tachycardia (VT) not due to a transient or a reversible cause; 2) spontaneous sustained VT; 3) syncope of undetermined origin with clinically relevant, hemodynamically significant sustained VT or VF induced at electrophysiologic study when drug therapy is ineffective, not tolerated, or not preferred; ; 4) patients with prior myocardial infarction (MI) at least 40 days previously with a left ventricular ejection fraction (LVEF) less than 35% who are in New York Heart Association (NYHA) class II or III; 5) patients with nonischemic dilated cardiomyopathy with a LVEF less than or equal to 35% who are in NYHA class II or III; 6) patients with prior MI at least 40 days previously with a LVEF less than 30% who are in NYHA class I; and 7) patients with nonsustained VT due to prior MI with a LVEF less than 40% and inducible VF or sustained VT at electrophysiological study.

 

Citation: Wilbert S Aronow (2014) Indications for Implantable Cardioverter-Defibrillator Therapy and Recommendations for Implantable Cardioverter-Defibrillator Therapy in Patients not Included or not Well Represented in Clinical Trials. J Cardiovasc Dis Diagn 2: e106.

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