Many diseases are associated with abnormal blood flow such as stroke, peripheral arterial disease (PAD), and cancer. An occlusive stroke/PAD is an interruption of the blood flow to the brain/skeletal muscle, which may impair or even destroy the cerebral/muscular function. The abnormal vasculature and/or high metabolic demand in tumors may generate abnormal blood flow compared to the surrounding normal tissues. The various treatments for these diseases share the common goal of modifying blood flow in some way. These treatments include improving blood flow to the ischemic tissues or shutting down the blood flow to cancer cells. Therefore, measurement of tissue blood flow may provide information for diagnosis of various tissue diseases, and for monitoring of therapeutic effects.
Yu G (2012) Near-Infrared Diffuse Correlation Spectroscopy (DCS) for Assessing Deep Tissue Blood Flow. Anatom Physiol 2:e115.