Ochronosis is a known disease since Virchow figured out the clinical presentation in1866. Reid published the cartilage disorder involving with early onset osteoarthritis . Alkaptonuria is characterized by deposition of polymerized homogentisic acid pigment in connective tissue and is called as ochronosis . Ochronosis arises in approximately 50% of alkaptonuric patients .The lack of homogentisic acid oxidase enzyme is the reason of this deposition. It is a rare autosomal recessive metabolic disorder which has an incidence one per 2-5 million live births .