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Deficits in information processing speed are common in individuals with MS, but adequate detection of such is fraught with methodological difficulties. The Computerized Test of Information Processing (CTIP) is a relatively new measure that addresses some of these methodological concerns. The equivalency of a desktop and fMRI scanner version of the CTIP at detecting cognitive impairment and monitoring cognition over time was examined in a sample of individuals with multiple sclerosis (MS). Six individuals with a confirmed diagnosis of MS completed both the desktop and a modified scanner version of the CTIP at baseline and 3 year follow-up. No participant demonstrated reliably significant change in performance over time. A modified version of the CTIP adapted for use in an fMRI environment holds promise for the detection of information processing speed deficits in MS.
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