alexa Molecular Profiling of Potential Human Prostate Cancer Stem Cells

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Molecular Profiling of Potential Human Prostate Cancer Stem Cells

While the cellular origin of cancer remains unresolved, two long-time competing hypotheses, namely the “stem cell theory” and the “de-differentiation theory” of cancer, have enticed new interest because of recent advances in stem cell research and molecular oncology. It has long been noted that the disciplines of developmental biology and oncology share interests in common factors, such as genetic/environmental and dietary factors, which are associated with teratogenesis and carcinogenesis. The ideas that cancer is a “disease of cell differentiation”, a “stem cell disease” and “oncogeny as partially-blocked ontogeny” depend on the original target cell, that ultimately leads to cancer, being an adult stem cell. Even though each tumor contains genotypic/phenotypic–diverse cells, they all seem to have originated from a single “cancer stem cell”, in that they are clonally-derived.

Miceli V, Cocciadiferro L, Maurizio Z, Kang KS, Trosko JE, et al. (2011) Molecular Profiling of Potential Human Prostate Cancer Stem Cells. J Stem Cell Res Ther S7:001. doi: 10.4172/2157-7633.S7-001

 
  • Share this page
  • Facebook
  • Twitter
  • LinkedIn
  • Google+
  • Pinterest
  • Blogger
 
adwords