The treatment of oral cancer consists mainly of surgical resection, chemotherapy and radiotherapy. The majority of patients with locally advanced oral cancer undergo surgical resection which, to maintain an optimal surgical margin, often involves facial deformities and loss of oral functions such as drinking, mastication, swallowing, and speaking. On the other hand, patients treated with chemotherapy and radiotherapy typically have severe stomatitis and pharyngitis, which make eating difficult. Furthermore, a majority of oral cancer patients are nutritionally compromised at the time of diagnosis because of dysphagia or odynophagia from the primary tumor.
Hiraoka SI, Adachi M (2012) New Strategies for Perioperative Nutrition Control for Patients With Locally Advanced Oral Cancer. Dentistry 2:e109.