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Morgellons disease (MD) is an emerging dermatological disorder and multisystem illness. The disease is characterized by unexplained dermopathy associated with formation of unusual filaments found both subcutaneously and emerging from spontaneously appearing, slow-healing skin lesions. Filaments associated with MD appear beneath unbroken skin, thus demonstrating that they are not self-implanted. Filaments have been observed protruding from and attached to a matrix of epithelial cells. This finding demonstrates that the filaments are of human cellular origin and are not textile fibers. These filaments have not been matched with known textile fibers, and dye-extracting solvents have failed to release coloration; the fibers are also very strong and heat resistant. MD filaments are physically and chemically consistent with keratin, a biofiber produced in the epithelium by keratinocytes. A recent report from the Centers for Disease Control and Prevention (CDC) confirmed that these filaments have a protein composition that is consistent with keratin.
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