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Bacterial components are well-established to have an immunomodulatory eff ect. Del-Immune V® is a US Food and Drug Administration-registered food supplement containing dry fermental cell lysate and DNA fragments of the probiotic strain Lactobacillus rhamnosus V (DV Strain). Th e product contains fragments of DNA and cell peptidoglycan of the lactic acid bacteria. Preliminary experimental clinical data suggest that components of Del-Immune V® may be eff ective in stimulating innate immunity. However, the mechanisms of activity of the formulation have not yet been verified.