Worldwide, cervical cancer is the second most common cancer in women, according to the World Health Organization (WHO), every year 5,000 women worldwide develop cervical cancer and 270,000 die, 80% of these occur in developing countries. High-risk Human Papiloma Virus (HPV) is the primary factor in cervical tumor genesis. Studies have shown that approximately 40% of sexual active women have high-risk HPV infection, but in 1% of patients, the HPV infection cannot be cured and ultimately leads to cervical cancer. These findings suggest that the immune system play a critical role in the incidence of cervical cancer.

Citation:

Moreno-Eutimio MA, Acosta-Altamirano G, Vargas-Hernández VM (2013) Expression of Toll-like Receptor 9 in Cervical Intraepithelial Neoplasia from Mexican Women. J Cytol Histol 4:181.

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