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Case of Severe Unconjugated Hyperbilirubinemia in a Neonate

Unconjugated hyperbilirubinemia can be caused by bilirubin overproduction (i.e. hemolysis), impaired hepatic bilirubin uptake (i.e. reduced hepatic blood flow or certain drugs), or impaired hepatic bilirubin conjugation (i.e. Gilbert syndrome and Crigler-Najjar syndrome Types I and II).

 

Citation: Abell R, Monteleone B, Chawla A (2012) Case of Severe Unconjugated Hyperbilirubinemia in a Neonate Heterozygous for Gilbert Syndrome. Hereditary Genet 1:114.

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