This article explains that the clinical and imaging findings congruent with CBS-AD are not easy to define prospectively, especially in the presence of discordant clinical and imaging elements. In the present case, amyloid imaging was positive, hence providing a tie breaker in favor of AD pathology. However, it is important to acknowledge that amyloid deposition inevitably occurs in the aging process of all cognitively normal individuals, and that a positive scan does not automatically translate into AD.Hence, in the interpretation of positive scans, it is essential to consider every clinical and imaging element that may weigh in the favor of a clinical diagnosis of AD.
Citation: BensaÃ¯dane MR, Fortin M-P, Damasse G, Chenard M, Dionne C, et al. (2014) Clinical Utility of Amyloid Imaging in a Complex Case of Corticobasal Syndrome Presenting with Psychiatric Symptoms. J Neurol Disord 2:194