The clinical pharmacist professional is enormously growing worldwide. The need for the practicing clinical pharmacist became an inevitable in all healthcare settings. This gain of reputation and recognition has come from the emerging needs for safe, economic and rational use of pharmaceuticals. One of the most vital and proactive role of clinical pharmacist is the application of pharmacovigilance principles in day-to-day clinical practice. The establishment of pharmacovigilance surveillance schemes on use of pharmaceuticals is mandated by the substantial escalated diverse new drug-entities, presence of multiple co-morbidities and inappropriate and problematic poly-pharmacy.