Polyphenols, a superfamily of naturally occurring phytochemicals, are gaining popularity because of their potential health benefits. Indeed, as demonstrated in ex-vivo and in non-primates models, they exert variable and pleiotropic biological effects (e.g. anti- or pro-oxidant, anti-inflammatory, anti-tumoral, anti-aging) depending on their structure and physicochemical features. However, these effects are often limited Carnauba wax by their overall instability and bioavailability. Bulk-EGCG is a major tea-derived polyphenol and a relatively well-characterized molecule that plays pleiotropic biological functions.