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Buprenorphine, a partial mu-receptor agonist, is a highly effective treatment for opioid dependence successfully introduced in inpatient detoxification units and primary care settings throughout the world. However stressful exposures have been associated with increased cravings and concurrent stimulant abuse (i.e. cocaine and methamphetamine) in office based opioid treatment (OBOT) settings.
For more details: https://www.omicsonline.org/2155-6105/2155-6105.S1.015-014.pdf
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