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Chemo Proteomics, a Valuable Tool for Biomarker and Drug Discovery

Discovery and development of new drugs and therapeutic agents is greatly aided by knowing the identity of proteins affected by small molecule drugs, the drug targets. Understanding the drug targets is the key factor in development and optimization of drug candidates for high efficacy and low toxicity. Currently, large majority of the small molecule drugs on the market affect a small fraction of potential drug targets of the human proteome. In recent estimates the number of druggable targets is significantly higher, possibly as much as one order of magnitude higher, than the current number of protein targets through which small molecule drugs mediate their effect.

Citation: Marjeta U (2014) Chemo Proteomics, a Valuable Tool for Biomarker and Drug Discovery. Mol Biol 3:e117. doi: 10.4172/2168-9547.1000e117

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