Nucleosome-assembly protein-related proteins (NRPs) are multifunctional proteins having histone chaperone  and histone phosphatase inhibitor  properties and being implicated in root meristem maintenance , mitotic regulation , chromatinmediated gene silencing , genotoxic sensitivity  and homologous recombination . The drosophila homologue of plant NRPs, the SET protein, has been shown to accumulate at heat-shock gene loci in response to increased temperature where it co-localized with Ser10-phosphorylated histoneH3 . It was therefore hypothesized that the drosophila SET protein prevents phosphatase2A (PP2A)- mediated histoneH3 dephosphorylation and contributes to chromatin modifications facilitating heat shock protein gene transcription .
Citation: Bíró J, Domoki M, Fehér A (2013) NAP-Related Protein 1 (Atnrp1) Overexpression Increases the Heat Tolerance of Arabidopsis Cells/Plantlets. J Plant Biochem Physiol 1:115. doi: 10.4172/2329-9029.1000115