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Stem Cells and Regenerative Medicine has been focused to be the major counterparts in the current research perspectives. Clinical trials have shown its efficacy as well as its instability. Reproducibility is found to be lacking nevertheless has enabled promise to certain subjects. Physician’s interests have also been unstable since several physicians show differences in their understanding and opinion. Though Stem cells has been projected to be an experimental therapy for those incurable diseases which otherwise do not have any options, this review focuses on ideas and experiences along with the dilemma existing among physicians to undertake stem cells as routine clinical practice.