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Arresting Prostate Cancer Growth by Targeting the Androgen Receptor and MAGE-A11

Important questions concerning the hormonal regulation of prostate cancer growth include: Can the androgen receptor (AR) drive prostate tumor growth independent of androgen, and can drug therapies that target androgen biosynthetic enzymes provide a long term cure for prostate cancer?

 

Citation: Bowen RS, Knab AM, Hamilton AT, McCall JR, Moore-Harrison TL, et al. (2012) Effects of Supraphysiological Doses of Sex Steroids on Wheel Running Activity in Mice. J Steroids Horm Sci 3:110. doi: 10.4172/2157-7536.1000110

 

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