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Clinical and Radiological Considerations for Incorporating Computed Tomographic Colonography into Colorectal Cancer Screening Programs

Colorectal cancer is the third most common type of cancer and the second leading cause of cancer death in the United States. Clinical evidence amassed over the last several decades indicates that routine screening, compared to no screening, detects the disease at an earlier stage, and reduces the incidence of colorectal cancer by interrupting the adenoma-to-carcinoma sequence in colon polyps through colonoscopy-guided polypectomy and thus reduces mortality. Guidelines for screening include fecal occult blood testing, sigmoidoscopy, colonoscopy and – most recently – computed tomographic colonography.

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