alexa Vitamin Transport Diseases of Brain: Focus on Folates, Thiamine and Riboflavin

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Vitamin Transport Diseases of Brain: Focus on Folates, Thiamine and Riboflavin

Background: In the last decade, childhood neurological disorders involving inadequate transport of thiamine, riboflavin or folates into brain have been defined. These involve two transporters of folate (the folate receptor α or the proton-coupled folate transporter), one of thiamine and two of the six riboflavin transporters. Depending on the mutations involved, without a specific diagnosis and treatment, the phenotypes vary from mild to severe and fatal.

Citation: Spector R (2014) Vitamin Transport Diseases of Brain: Focus on Folates, Thiamine and Riboflavin. Brain Disord Ther 3:120. doi: 10.4172/2168-975X.1000120

 
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