alexa Facile Synthesis of 1-(substituted phenyl)-2-phenyl-4-(substituted benzylidine)-imidazole-5-ones and Antifungal Activity Studies against Phytopathogens

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Facile Synthesis of 1-(substituted phenyl)-2-phenyl-4-(substituted benzylidine)-imidazole-5-ones and Antifungal Activity Studies against Phytopathogens

A series of five new 1-(substituted phenyl)-2-phenyl-4-(substituted benzylidine)-imidazole-5-one derivatives (or) 5(4 H )-imidazolones have been synthesised adopting 3 o A Zeolite as catalyst. These compounds were assayed for their antifungal activity on three different selected phytopathogens which disparately affects the Jowar crop (Sorghum Vulgare) of Poaceae family. Among the tested molecules, compound 18 exhibited potent inhibitory activity when compared to the Bavistine (Positive control).

Citation: Voosala C, Yarla NS, Nakka MR, Vidavaluri S (2013) Facile Synthesis of 1-(substituted phenyl)-2-phenyl-4-(substituted benzylidine)-imidazole-5-ones and Antifungal Activity Studies against Phytopathogens. Med chem 4:303-305. doi: 10.4172/2161-0444.1000156

 
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